Friday, January 1, 2010

Candida Albicans Life Cycle

Candida albicans life cycle is dimorphic. That means that this life cycle includes two stages (di indicates this) - yeast stage and hyphae stage. Candida produces hyphae and pseudohyphae (the last can give rise to new Candida cells by budding).

There are many species of Candida that are involved in different forms of candidiasys. And different forms of yeast infections cause different symptoms.

Candida albicans can be found in like 40 to 80% of normal, healthy humans. Normally you can find it on the skin, in the mouth, in the vagina, in the intestines and in the respiratory system. The body immunity and normal flora from the skin and from the guts prevents Candida overgrowth and symptoms appearance.

Yeast infection symptoms are developed when the cellular immunity goes low because of different causes or normal intestinal flora, consisting of good, friendly bacteria is destroyed (by antibiotics in most cases).

In most cases skin or mucosa is affected by yeast infection, but in some cases, candida can cause life threatening infections like pneumonia, septicemia or endocarditis in immuno-compromised patients. The ability of causing the infections, most probably is conditioned by the human organism properties (i.e. low immunity, lack of friendly bacteria, abnormal physiology) and not by Candida aggressivity.

Depending on external environment, candida can form spores, which are called chlamydospores. Spores are more resistant to nocive environment and are very usefull for determination of the yeast species. Spores are also considered by some mycologists as a part of candida albicans life cycle.


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